Research Articles

Pulmonary Hypertension in Sickle Cell Disease Patients: Correlation of TRV Jet with Serum NT-Pro BNP Concentration

ABSTRACT: Objectives: The aim of this study was to determine the prevalence of pulmonary hypertension [PH] and correlate it with the laboratory markers of hemolysis and serum NT-pro brain natriuretic peptide [BNP] concentrations in Sickle cell disease [SCD] patients from Oman.

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Invitro Antibacterial Activity of Ethanolic Extracts of Dietary Spices Against Clinical Isolates.

ABSTRACT: The invitro antibacterial activity of ethanolic extracts of three dietary spices Coriandum sativum (Coriander), Curcuma longa (Turmeric) and Capsicum annuum (Red chili) were investigated by well diffusion method against clinical isolates which include Gram positive (Enterrococcus spp., Staphlococcus aureus) and Gram negative (Pseudomonas aeruginosa, Salmonella typhi, Escherichis coli, Proteus spp., Klebsiella pneumonia and Acinetobacter baumannii) as well as by minimal inhibitory concentration and by microdilution method. Moreover, killing time of each extract was also calculated against Escherichia coli.

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LABs Responsible for Enhancing Antibiotic Susceptibility Pattern and Gene Transference.

ABSTRACT: Probiotics are gram positive organisms considered beneficial for combating with various pathogens. Most of them are antibiotic resistant, giving an idea that they may be carrier of r-plasmids. Our aim of the study was to determine the proportion of LABs that associate with r-gene transference as well as in boosting up antibiotic susceptibility range. For that we isolated probiotic cultures of Streptococcus, Lactobacillus, and Leuconostoc from milk sample, and checked the susceptibility pattern of isolated probiotics and pathogens (test organisms) against carbepenem. Results showed all LABs are resistant, while most of the pure test organisms were sensitive, after that these pathogens were treated with Labs coated disc that was prepared by the Kirby Bauer method. These LAB treated organisms were again checked with carbepenem to check the susceptibility pattern, this whole protocol was carried out on Muller Hinton Agar (MHA) plate. According to our results test organisms treated with Streptococcus and Lactobacillus species occurred with a 20% and 1% of resistivity, while organisms treated with Leuconostoc species enhanced the sensitivity 66% and streptococcus 1%, whereas Lactobacillus did not show any change in antibiotic spectrum

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Descriptive Controlled Study Regarding the Effects of Negative Chronotropic Agents on Lowering Heart Rate and Morning Surge in a Tertiary Care Hospital.

ABSTRACT: Objective: To determine the optimal therapy for lowering the heart rate (HR) of cardio-compromised patients by observing the effect of negative chronotropic agents.

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